Locoregional Interaction of Ixabepilone (Ixempra) After Breast Cancer Radiation
نویسندگان
چکیده
منابع مشابه
Ixabepilone (ixempra), a therapeutic option for locally advanced or metastatic breast cancer.
Ixabepilone (Ixempra) is a member of a new class of cytotoxic agents, the epothilones. Epothilones promote tubulin polymerization in vitro and demonstrate antitumor activity. This article reviews the preclinical and clinical data that have led to the approval of ixabepilone for patients with locally advanced or metastatic breast cancer for whom anthracycline and taxane treatments have failed.
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Triple-Negative Breast Cancer After Breast-Conserving Surgery and Radiation I read with interest the article by Freedman et al investigating the results of radiation on the local control of triple receptor-negative (TN) breast cancer (negative estrogen [ER], progesterone [PR], and HER-2 receptors). The authors compared 3 different groups defined by receptor status as follows: Group 1: ER or PR ...
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BACKGROUND Enhancer of zeste homolog 2 (EZH2), a member of the polycomb group proteins, has been shown to promote cancer progression and breast cancer stem cell (CSC) expansion. Breast CSCs are associated with resistance to radiation in inflammatory breast cancer (IBC), a rare but aggressive variant of breast cancer. In this retrospective study, we examined the clinical role of EZH2 in locoregi...
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PURPOSE This study aims to explore gene expression profiles that are associated with locoregional (LR) recurrence in breast cancer after mastectomy. PATIENTS AND METHODS A total of 94 breast cancer patients who underwent mastectomy between 1990 and 2001 and had DNA microarray study on the primary tumor tissues were chosen for this study. Eligible patient should have no evidence of LR recurren...
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AIM Lipofilling is a part of the clinical practice for breast reshaping in patients who underwent surgery for breast cancer. A strong debate in the Literature is open about a higher risk of cancer relapse caused by growth factors produced by adipocyte stem cells after their engraftment in the recipient tissue. Nowadays there is no agreement over the use of autologous fat tissue for the correcti...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2013
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2012-0348